Now that July has arrived, the Carolina Panthers are preparing for training camp and the start of the 2025 season. This period is an opportunity to assess their opponents’ offseason activities and how these might affect upcoming matchups.
One notable opponent is the San Francisco 49ers, whom the Panthers will face in Week 12 in Santa Clara on November 24 at 8:15 p.m. Historically, the Panthers lead the all-time series against the 49ers with a record of 13-9 overall. Their last encounter was during Week 5 of the 2022 season, resulting in a loss for the Panthers with a score of 37-15.
The previous season saw challenges for the 49ers as they ended with a record of 6-11. Despite ranking fourth in total offense and eighth in total defense, injuries to key players like Christian McCaffrey and Brandon Aiyuk affected their performance.
In response to last year’s difficulties, several personnel changes were made by the team. The offseason saw them trade for DE Bryce Huff and sign various players including TE Luke Farrell and QB Mac Jones. Additionally, they drafted DE Mykel Williams among others.
A significant move was extending quarterback Brock Purdy’s contract to five years worth $265 million. However, they also traded Deebo Samuel to Washington and lost other key players through free agency.
Looking ahead to this year’s matchup against San Francisco, it marks Carolina’s return to Monday Night Football since Week 2 of 2023. The game will be crucial as both teams aim to capitalize on their offseason changes.
